The Electronic Transaction Act B.E. 2544 (2001) (ETA) supports the legal effect of the e-signature much like the traditional signature on paper, provided that the criteria of being an e-signature under the ETA is met. The Electronic Transaction Development Agency recently published a recommendation on the ICT standard for electronic transactions in June 2023. This is also subject to further general legal formalities for each type of finance document (such as security documents) to ensure the validity of such document.
In a case where the law requires the signature of a witness, it is arguable whether the witness has to be "present physically" at the same place as the parties that are signing the agreement, or whether electronically witnessing from a distance via a live video call would suffice. Both e-transaction-related laws must be met and general legal formalities for each document/transaction must be followed to ensure the legal validity of such document/transaction.
The registration system of mortgages in Thailand currently requires documents to be executed in the presence of the officer in wet ink.
Other forms of security may be executed with an e-signature, but the legal requirements in relation to the perfection requirements, as mentioned in question 11 of the section "If taking security" will still apply.